american board gynecology & obstetric mcq

1. A patient with non-metastatic gestational trophoblastic disease can be treated with weekly intramuscular injections of which of the following agents ?
   Cyclophosphamide
   Carboplatinum
   VP-16 (etoposide)
   Actinomycin D
   Methotrexate
2. Five-year survival rates of patients with low-risk, non-metastatic gestational trophoblastic disease approaches ?
   100%
   75%
   50%
   25%
   5 to 10%
3. Comparing complete hydatidiform moles gestations, complete and partial moles are more likely to demonstrate all of these characteristics except ?
   more likely to require chemotherapy after evacuation for gestational trophablastic disease
   more likely to present with a uterus large for dates
   more likely to present with theca lutein cysts
   more likely to 'have focal rather than diffuse trophoblastic proliferation
   more likely to diffuse hydopic swelling of villi
4. A woman experiencing a molar pregnancy has an increased risk of which of the following in subsequent gestations ?
   Stillbirth
   Prematurity
   Congenital malformations
   Recurrent molar gestation
   Cancer later in life

5. The most likely karyotype of patient with a complete mole would be ?
   46, XX
   46, XY
   Diandric triploidy
   Triploidy with two haploid sets of maternal origin
   Aneuploidy
6. The most likely karyotype of patient with a partial mole would be ?
   46, XX
   46, XY
   Diandric triploidy
   Triploidy with two haploid sets of maternal origin
   Aneuploidy
7. A woman with a complete mole is most likely to present with which of the symptoms ?
   Vaginal Bleeding
   Excessive uterine size
   Hypermesis
   Prominent theca lutein cysts
   Pre-eclampsia
8. A patient with a complete mole is found to have sizeable ovarian cysts that are presumed to be theca lutein cysts. All of the following are true about theca lutein cysts EXCEPT ?
   Such cysts arise more frequently in patients with complete moles
   Theca lutein cysts are more likely seen in patients with very high hCG levels
   Cysts are filled with serious or serosanguinous fluid and are usually bilateral
   Often require active management with surgical intervention
   Patients with large theca lutein cysts may be at increased risk for postmolar persistence of disease